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KMID : 0358320060470040436
Korean Journal of Urology
2006 Volume.47 No. 4 p.436 ~ p.439
Ureteral Obstruction Caused by Periureteral Tuberculous Granuloma after Intravesical BCG Therapy for Superficial Bladder Tumors
Nam Sang-Bok

Park Jung-Suk
Kim Jae-Jun
Park Jun-Tag
Nam Sam-Keuk
Abstract
Bacillus Calmette-Guerin(BCG) is an attenuated strain of Mycobacterium bovis(M. bovis) that has been used to treat transitional cell carcinoma. Since the initial report by Morales and associates on the use of intravesical BCG for the treatment of recurrent superficial bladder tumors, intravesical therapy with BCG has proved to be more effective for prophylaxis and the treatment of superficial bladder tumors and carcinoma in situ than most of the standard chemotherapeutic agents. While the majority of patients tolerate BCG treatments well, a number of adverse reaction(e.g., fever, hematuria, dysuria, nausea and malaise) have been reported. More serious complications occur on rare occasions and they include pneumonitis/hepatitis, ureteral obstruction, renal abscess and sepsis. We report here on a case of ureteral obstruction that was caused by periureteral tuberculous granuloma after intravesical BCG therapy for superficial bladder tumors, and the condition required distal ureterectomy & ureteroneocystostomy. (Korean J Urol 2006;47:436-439)
KEYWORD
Mycobacterium bovis, Bladder neoplasms, Granuloma, Ureteral obstruction
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